It takes approximately 1.3 Bi USD and a median 8.3 years to bring new drugs to market because approximately 97% of all drug candidates will fail during drug discovery and development. Supplementing or replacing clinical trials with virtual patients (i.e., digital representations of human disease biology, e.g., digital twins in medical devices) is a viable solution that is gaining market and regulatory support for example in rare diseases where few patients exist or in patient populations with ethical concerns such as young children or pregnant mothers. Douglas McCloskey earned his PhD in bioengineering from UC San Diego in 2017, receiving the Siebel Scholars Foundation grant for his work on metabolism and evolution. From 2018 to 2021, he was a principal investigator at the Technical University of Denmark, leading a team to automate the design-build-test-analyze cycle for developing cell factories and therapies. As Chief Scientific Officer and co-founder at AliveX Biotech (2021–2022), he led the creation of an AI and Omics systems immunology platform for drug discovery and patient stratification. Currently, he is a PI at BioMed X, partnering with Sanofi to develop a virtual patient model to predict drug efficacy. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx
More from TED
- 14:50Change Is the Only Constant | Jonathan Jai | TEDxICEASLife is unpredictable, chaotic, and often feels beyond our control. This TEDxICEAS talk dives deep into the relentless reality of change—how it challenges us, shapes us, and demands resilience. It explores the common illusion that we can control our destiny, and why embracing change as a battlefield is the truest way to win.Jonathan Thomas Jai is a Bangalore-based writer and researcher specializing in international relations, public policy, philosophy, and psychology. His work merges political analysis with philosophical inquiry, exploring governance, power, and the psychology behind leadership.A student of International Relations,Peace and Public Policy at St Joseph’s University, he currently writes for OneIndia, Dailyhunt, and Mathrubhumi English, covering global politics and policy. As a Research Analyst for MP K. Sudhakaran, he contributes to policy formulation and legislative discussions, gaining firsthand experience in governance.Jonathan actively engages in public debates and policy forums along with philosophical and political discussions offering critical insights into democracy, ethics, and global affairs. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx
- 17:23Persistence - Fighting for what you Love | Karen Vincent | TEDxICEASFrom humble beginnings to navigating the chaos of school corridors, college adventures, and corporate realities—this TEDxICEAS talk is a candid, funny, and inspiring journey through the stages of growing up in today’s world. Making the world a happier place one joke at a time, with content that resonates with audiences of all ages, Karen found her passion and love for the stage one day and never went back to being mediocre. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx
- 17:51Traffic Management & Road Safety | Dr. M A Saleem IPS | TEDxICEASExplore the pressing realities of traffic management and road safety in one of India's fastest-growing urban areas. This TEDxICEAS talk sheds light on the challenges posed by rapid vehicle growth, limited infrastructure, and the increasing toll of road accidents in Bengaluru and across India. Dr. M. A. Saleem’s illustrious career in the Indian Police Service (IPS) began in 1993, following his selection through the All India Civil Service Examination. His tenure with the Karnataka State Police has been marked by versatility and excellence, serving in 26 various capacities across the state. His roles have ranged from Superintendent of Police in districts like Udupi and Hassan to more senior positions such as Inspector General of Police, Eastern Range, Commissioner of Police in Mysore City and Special Commissioner of Police in Bengaluru.He has headed Anti-Corruption Bureau, Crime and Administration wings of Karnataka State Police. Currently, he holds the esteemed position of Director General of Police, Criminal Investigation Department (CID) Karnataka, where important and sensational cases get investigated. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx
- 26:31Saving, Serving, and Succeeding: A Life Beyond Limits | Pralhad Kulkarni | TEDxICEASThis powerful TEDxICEAS talk shares a journey of resilience, motivation, and transformation against all odds. Born into poverty, the speaker’s story begins with the struggle to even mail a resume and evolves through service in the Air Force, followed by a career in the Karnataka Police as a Sub Inspector. He began his journey in the Indian Air Force, instilling discipline and dedication before transitioning to the Karnataka Police as a Sub-Inspector. Balancing duty and ambition, he prepared for the KPSC KAS exams, eventually becoming an Assistant Commissioner of Commercial Taxes. His journey from an Aircraftman Under Trainee to a civil servant showcases perseverance and resilience. Through real-life experiences and humor, he inspires others to overcome challenges and explore careers in defense and government services. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx
- 22:38Power of ‘What Next?’ — Finding Purpose | Pramod Chandrashekar | TEDxICEASEvery journey begins with a why—the reason that fuels the first step and keeps us going when the path feels uncertain. This TEDxICEAS talk shares a deeply personal story of loss, learning, and transformation, revealing how pain can spark purpose and how mistakes can become powerful lessons. Pramodh Chandrashekar is a changemaker on a mission. He founded the Last Ripple Foundation, India’s first initiative to create special biodegradable urns that turn ashes into living memory trees. His foundation also provides 24/7 pet funeral services, helping families say goodbye with dignity. As the Founder & CEO of COINCONTRA, he’s making personal finance easy and accessible for everyone. A serial entrepreneur, lawyer, and author, Pramodh has delivered 100+ speeches, written books—all to create a lasting impact on people’s lives. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx
- 8:14The Bar Starts at Home | Rida Khan | TEDxICEASWhat shapes a child’s confidence, values, and sense of belonging? This TEDxICEAS talk explores the profound truth that the foundation of who we become is built at home. It’s here, in the everyday moments of attention, care, and conversation, that self-worth takes root—or withers. Rida Khan, is a content creator who specializes in entertainment and relatable content. With her witty humor and down-to-earth style, she captivates her audience by sharing everyday situations in a fun and engaging way. From comedic skits to relatable commentary on daily life, Rida’s content resonates with young adults who appreciate her authenticity and playful personality. Whether she’s poking fun at common experiences or delivering light-hearted entertainment, Rida brings joy and laughter to her followers, creating a space where people can connect through shared humor and relatable moments. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx
